Preheat oven to 375 degrees.
Poke potatoes with a fork. Place in preheated oven and bake for 30 - 40 minutes or until soft. (Cooking time will vary based on size of potatoes.) Meanwhile, in a large skillet, add the ground turkey. Break up into small pieces as it cooks. Once cooked, drain excess fat, if needed. Season with chili powder and cumin, garlic powder and cayenne, if using. Stir to fully incorporate.
When potatoes or done cooking, remove from oven. When cool enough to handle, cut open top to let steam out. Top potatoes with taco turkey meat, chopped tomatoes or salsa and avocado. Add optional garnishes if desired.